更新时间：2026-10-30 14:08:42
产品货号：KS131
ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in l
ACACA | ACC1 Recombinant Rabbit mAb
Host: Rabbit Isotype: IgG
Clonality: Recombinant CloneNo.: 2B5
GeneID: 32 SWISS: Q13085
Target: ACACA | ACC1
Purification: affinity purified by Protein A
Concentration: 1mg/ml
Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50%
Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated
freeze/thaw cycles.
Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme
system. ACC is a biotin-containing enzyme which catalyzes the
carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step
in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in
lipogenic tissues. The enzyme is under long term control at the
transcriptional and translational levels and under short term
regulation by the phosphorylation/dephosphorylation oftargeted
serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants
divergent in the 5' sequence and encoding distinct isoforms have
been found for this gene
